Batch production of the S/253 series started in March 2008. 55 machines were built in Vado Ligure, Italy, to be placed on their 1668 mm bogies when entering Spain. The remaining 45 machines will be sent to Villaverde Bojo as kits, of which the parts will come from various Bombardier factories from all over Europe.
On 20.01.2009, the first five units (253 001-005) were officially handed over to Renfe. 253 011 was the first locomotive to be completed in Spain. In July 2010 the handing over of the very last locomotive will take place. 253 100 will be a unit from the Spanish assembly line.